Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

This is a preview. Log in through your library . Abstract Gene expression relies on quality control for accurate transmission of genetic information. One mechanism that prevents amino acid ...

For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein ...

Daisuke Kiga, Kensaku Sakamoto, Koichiro Kodama, Takanori Kigawa, Takayoshi Matsuda, Takashi Yabuki, Mikako Shirouzu, Yoko Harada, Hiroshi Nakayama, Koji Takio, Yoshinori Hasegawa, Yaeta Endo, Ichiro ...

Hidden within the genetic code lies the "triplet code," a series of three nucleotides that determine a single amino acid. How did scientists discover and unlock this amino acid code? Once the budding ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of ...