Monoclonal antibodies are widely used to treat diseases ranging from cancer to autoimmune disorders. The safety and efficacy of these biologic drugs depend on maintaining their correct ...

Of the nine treatments and preventives for COVID-19 authorized for emergency use by the Food and Drug Administration, three are drugs made from so-called monoclonal antibodies. Such drugs provide ...

In a recent study published in Science Translational Medicine, researchers evaluated the differential humoral immune response to two coronavirus disease 2019 (COVID-19) vaccines - messenger ...

Effective antibody responses against HIV are rare both during natural infection and after vaccination. As a result, many research groups have focused their efforts on identifying and characterizing ...

Monoclonal antibodies are among the most widely used biologic medicines, with applications ranging from cancer treatment to ...

A dual-action HIV antibody–drug conjugate forces Env to open, then blocks it, boosting virus neutralization up to tenfold in the lab.

Monoclonal antibodies have proved effective in the prevention and treatment of Covid-19. Their effectiveness depends on the recognition of specific structures on the surface of the viral spike protein ...

Doctors of Meenakshi Mission Hospital has successfully used monoclonal antibody therapy to treat Anti-Glomerular Basement Membrane disease, helping a patient recover kidney function and come off ...

In the aftermath of those cases, some practitioners have suggested means-plus-function claiming as one strategy to obtain antibody claims that are broader in scope than the specific antibodies ...

b) an Fc domain comprising amino acid substitutions M428L/N434S as compared to a human Fc polypeptide, wherein numbering is according to the EU index of Kabat, wherein said anti-C5 antibody with said ...