Charge heterogeneity in monoclonal antibodies can negatively impact binding affinity and potency, so it is critical to ensure that individual charge variants of biotherapeutic molecules are thoroughly ...
Avelumab (MSB0010718C; anti-PD-L1) in combination with other cancer immunotherapies in patients with advanced malignancies: The phase 1b/2 JAVELIN Medley study. Background: MGD009 is a B7-H3 x CD3 ...
Surface plasmon resonance (SPR) technology is expanding strategies for studying and analyzing binding kinetics, offering real-time, label-free analysis. Researchers at the “Developments in Protein ...
Fragment-based drug discovery (FBDD) has gained widespread recognition as a valuable approach in the search for lead drug candidates in drug discovery programs. It is utilized in conjunction with ...
SEATTLE, WA / ACCESSWIRE / December 2, 2020 / Aptevo Therapeutics Inc. ("Aptevo" or the "Company") (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immuno-oncology ...
Real-time, label-free binding analysis is often viewed incorrectly as an ‘art’ instead of a ‘science’. The Octet® SF3 system challenges this notion through user-friendly technology. The field of ...
Ryan Denomme, the CEO of Nicoya, speaks to News-Medical on their SARS-CoV-2 research using their SPR technology. At Nicoya, our mission is to improve human life by helping scientists succeed. Given ...
TEMPE, Ariz.--(BUSINESS WIRE)--Biosensing Instrument Inc (BI) introduced the SPRm 200, the world’s first commercially available surface plasmon resonance microscopy (SPRM) system. The new SPRm 200 is ...