Scientists have addressed a long-standing controversy behind the molecular players mediating calcium signaling, a biological process that coordinates a wide array of physiological responses, according ...
The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU ...
Neutralizing these regions completely abolished calcium regulation, and the mitochondria became overloaded with calcium. From this, the team found that EMRE-dependent matrix calcium regulation of MCU ...
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