Blocking a tumor antioxidant restored T cell activity and made some resistant cancers more responsive to immunotherapy in mice.

T-cell redirecting platforms function by enabling antigen-specific recognition or by colocalizing effector T cells with tumor ...

T cell immunity plays a pivotal role in the host defence against SARS-CoV-2, complementing humoral responses and contributing to viral clearance, disease modulation and long-term protection. Upon ...

As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as quickly, making people more susceptible to a variety of infections. To try to ...

T cells see only a small sample of the body’s proteins in the thymus, yet a machine learning model shows how they can still ...

Endothelial cells form the innermost lining of blood vessels and serve as active regulators of immune function by orchestrating T cell recruitment, activation and differentiation. Far from being a ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

An international research team led by Dr. Lucia Torres Fernández from the working groups of Professor Dr. Julie George and ...

A routine blood sample contains a diverse collection of immune cells that can reveal important clues about health and disease ...