Age is the single greatest risk factor for neurodegenerative disease, yet the cellular mechanisms that drive age-related protein accumulation in the brain remain incompletely understood. In ...

The capability to sort single cells of interest and to deeply characterize them has greatly added to our understanding of biology and disease states. Indeed, cell sorting has become an indispensable ...

From protein translation to mitosis, fundamental cellular processes are multifaceted and dynamic. Researchers seeking to understand the inner workings of a cell benefit from multidisciplinary ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

Researchers have found a molecular mechanism that prevents multiplication of potentially dangerous cells by measuring the duration of mitosis. They have shown that this mechanism -- the Mitotic ...

Researchers have uncovered a shared brain cell breakdown mechanism behind Alzheimer’s and Parkinson’s diseases, revealing how two different proteins can disrupt neurons in the same devastating way.

In a recent study published in the journal Nature, a group of researchers investigated how aging alters neuronal protein degradation, aggregation, and transfer to microglia, with a focus on synaptic ...