This figure depicts the complex regulatory network that maintains cellular cholesterol homeostasis. Metabolic and hormonal signals, including oxysterols, IGF-1, and FGF19, activate kinase cascades ...

"But it has now become clear that bile acids are more than just digestive aids; they act as signaling molecules, regulating cholesterol levels, fat metabolism, and more," said co-corresponding author ...

We have been taught to think of cholesterol as something that clogs arteries, spikes lab reports and comes with dietary guilt ...

Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...

Scientists have identified a previously unknown enzyme that acts as a biological “switch” controlling how the body makes and ...

A groundbreaking animal study has recently identified a novel enzyme that acts as a switch for fat synthesis. This discovery ...