Cell division is one of the most fundamental and complex processes underpinning life. In human cells, thousands of molecules ...

Treatment options for congenital heart disease are limited by the relative inability of mature cardiac muscle cells (cardiomyocytes) to generate new cardiomyocytes through proliferation after birth.

Because of the downregulation of dynein intermediate chain (IC) in cells depleted of NudCL, we tried to determine the protein levels of dynein IC in cells with NudCL overexpression. The result ...

In animal cells, mitotic cell division involves a highly coordinated series of events that lead to the formation of two daughter cells. It has been observed in many types of cells that actin and ...

Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. If unresolved, chromatin bridges can break in cytokinesis leading to micronuclei ...

Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. The mechanism underlying it is very complex. Until recently, the processes that lead to cleavage furrow ...

How does the cell organize multi-step cytokinetic processes to successfully separate cells after division? The final step in cell division is cytokinesis, where the cytoplasm divides into two after ...

As cell biologists, Université de Montréal professor Greg FitzHarris and his Ph.D. student Lia Paim are very interested in fertility and what happens inside the eggs and embryos of the mice they study ...