Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

A major obstacle to studying DNA replication is that it involves asynchronous and highly delocalized events. A reversible replication barrier overcomes this limitation and allows replication fork ...

Copy number control of DNA and centrosomes is essential for accurate genetic inheritance. DNA replication and centrosome duplication have been recognized as parallel key events for cell division. Here ...

The cells' attempt to restart the stalled replication fork subsequently prompted the formation of single-strand DNA breaks that necessitated repair with another protein known as poly (ADP-ribose) ...

A new study has uncovered a hidden step that helps the deadliest malaria parasite survive and multiply inside the human body. Researchers studying Plasmodium falciparum found that the parasite relies ...