UPTON, NY-Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is ...

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism. What’s not captured by this analogy is the fact that our DNA ...

COLUMBUS, Ohio — Chemists have calculated the structure of a very unusual molecule, one whose hyperactive atoms have earned it the nickname “the scrambler.” This highly caustic “protonated methane,” ...

Proteins adopt unstable, high-energy states that exist for fractions of a second but can have key biological roles. A new method of determining high-resolution structures of such states using a form ...

IN A DEVELOPMENT that promises to ease structural analysis of proteins, British researchers have found a way to determine protein structures by using only basic and easy-to-obtain data complemented by ...

The structure of a novel protein in the bacterium that is the most persistent pathogen in cystic fibrosis (CF) patients has been solved. Hauptman-Woodward Institute scientists Dr. Andrew Gulick, Eric ...

The single-stranded genetic material RNA is best known for guiding the assembly of proteins in our cells and carrying the genetic code for viruses like SARS-CoV-2 and HIV. But 40 years ago, scientists ...

Biologists have developed a computer modeling technique that lets them use cryo-electron microscopy to identify multiple possible structures that a protein can take. Cryo-electron microscopy (cryo-EM) ...

The results of this collaborative project overturn some conventional wisdom about how the DNA repair process works. DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts ...