The mammalian target of rapamycin (mTOR), an evolutionarily conserved serine/threonine protein kinase, serves as a central regulator of cell growth, proliferation, survival, and autophagy, and is ...

Cancer stem cells (CSCs) are suggested to be responsible for drug resistance and aggressive phenotypes of tumors. Mechanisms of CSC induction are still under investigation. Our lab has established a ...

Breast cancer is the second highest diagnosed cancer in women in the US and, as of 2020, the most commonly diagnosed cancer in women worldwide. 1 In 15–20 percent of these cases, the growth factor ...

Predictive and Prognostic Impact of Epidermal Growth Factor Receptor Mutation in Non–Small-Cell Lung Cancer Patients Treated With Gefitinib Sequential tumor biopsies from 33 patients were examined.

Metabotropic glutamate receptor-1: A new molecular target for the therapy of triple-negative breast cancer. Background: Brain metastases are the most common fatal ...