Previous studies in mice have reported that melanin-concentrating hormone (MCH) regulates bone calcification, an essential process in bone regeneration. However, the mechanisms by which MCH influences ...

Vitamin D3 is associated with multiple functions, including bone mineralization, regulation of cell growth, and immune and neuromuscular functions. The current article focuses on the role of vitamin D ...

In vertebrates, calcium is stored in bones, and its release is tightly regulated. Now, using fruit flies as a model organism, researchers at University of Tsukuba have shown that even animals without ...

Mitochondrial dysfunction and redox imbalance are central drivers of cardiovascular disease, contributing to impaired bioenergetics, oxidative stress, ...

Scanning electron microscope image showing pearl-like calcium granules (PCGs) accumulated within the lumen of the distal region of the Malpighian tubule in the fruit fly larva. Numerous PCGs, each ...