Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine and the sole member of the type II interferon class. Originally referred to as macrophage-activating factor, IFN-γ is now recognized as ...
Confirmed responses deepened with an average maximum tumor reduction from baseline of 89% and median time on treatment ...
A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers ...
During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or ...
In 2020, Ashley Harms, Ph.D., and University of Alabama at Birmingham colleagues published an Acta Neuropathologica study that used a mouse model to show that the alpha-synuclein pathology from ...
NeoPlus: A phase II study of neoadjuvant lenvatinib and pembrolizumab in resectable mucosal melanoma. Final clinical results and first translational correlates of a phase 2 trial of adaptively dosed ...
In the body, macrophage memory formation depends on a signaling molecule, or cytokine, known as interferon gamma. During an initial immune response, interferon gamma prompts macrophages to unwrap ...
Unlike antibody-producing B cells that help fight the current infection, the long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes. They reside there permanently and lie ...
Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results