Inositol 1,4,5-trisphosphate (IP3) signalling represents a ubiquitous mechanism by which extracellular stimuli are translated into precise intracellular calcium responses. Engagement of ...
In this common pathway, activated phospholipase C-β hydrolyzes the inositide PI 4,5-bisphosphate to release diacylglyerol and inositol 1,4,5 trisphosphate. IP3 opens specific Ca 2+ channels releasing ...
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