Scientists created a definitive E3 ligase atlas, resolving inconsistencies and enabling better disease research and drug design.

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration, ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Enzymes are vital to metabolism and drive countless biological processes in humans, plants, and industry. Yet, when overwhelmed by excess substrate, some enzymes slow down — a phenomenon known as ...

An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The ...

Reporting in Science, researchers at UC Santa Barbara, UCSF and the University of Pittsburgh have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, ...

A team of researchers led by the Walter and Eliza Hall Institute of Medical Research has produced the first systematic catalog of human E3 ubiquitin ligases, the enzymes responsible for tagging ...

Researchers have identified what may be the key molecular mechanism responsible for COVID-19 mortality -- an enzyme related to neurotoxins found in rattlesnake venom. An enzyme with an elusive role in ...

WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body. Published in Cell, the ...