Biologists have long suspected that aging is not just a slow, inevitable fraying of our cells but a process governed by specific molecular switches. A growing body of research now points to individual ...

Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and ...

Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes this protection, allowing harmful molecules to damage cell membranes and ...

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ...

Large-scale human genetics studies have shown that many risk variants for common and complex diseases sit in the non-coding ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...