Bioactive sphingolipids constitute a family of lipids, including sphingosine, ceramide, sphingosine-1-phosphate (S1P) and ceramide-1-phosphate. These molecules act on distinct protein targets, ...

Hypercaloric diets lead to the dysregulation of multiple lipid metabolic pathways, which contributes to the onset and progression of metabolic disease Lipidomic studies are starting to decipher the ...

Sphingolipids are important biological molecules, a class of lipids that have a backbone of sphingoid bases including sphingosine (aliphatic amino alcohol) or another structurally similar compound. In ...

Plasma ceramides and sphingomyelins with palmitic acid were linked to a 34% and 37% increased risk of sudden cardiac death (SCD) per higher SD of log sphingolipid levels, respectively. After looking ...

In a new study, the group of Johan Auwerx at EPFL's School of Life Sciences has made the first connection between muscular dystrophy and sphingolipids, a group of bioactive lipids. The study is ...

Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment ...

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this ...

Scientists have made a link between muscular dystrophy and a group of bioactive fats, the sphingolipids, which are involved in numerous cell functions and other diseases. In a new study, the group of ...

The global sphingolipids market is projected to be valued at USD 693.9 million in 2025 and is expected to reach USD 1,145.6 million by 2035, registering a CAGR of 5.1% during the forecast period. This ...

Solving the Riddle of the Sphingolipids in Coronary Artery Disease Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related ...