Background: A 12-week-old female presented with neonatal diabetes. Insulin therapy alleviated the diabetes, but the patient showed marked motor and mental developmental delay. The patient underwent ...

Moderate-risk patients with diabetes treated with a sulfonylurea appear to be at a higher risk of major adverse cardiovascular events than those who receive a dipeptidyl peptidase-4 (DPP-4) inhibitor, ...

SEATTLE ― Taking sulfonylureas sold as "street Valium" can lead to severe hypoglycemia that may result in emergency department (ED) visits, the latest of a handful of case reports suggests.

The prevalence of impaired awareness of hypoglycemia (IAH) is high among patients using sulfonylureas long term, according to a study published in the July/August issue of the Annals of Family ...

The subjects of the study were 228 diabetic children, 104 boys and 124 girls. All were under sixteen years of age. With few exceptions, all were in summer camps for diabetic children and leading ...

Sulfonylureas are a group of medicines used to treat type 2 diabetes. With type 2 diabetes, the body doesn’t use the hormone insulin properly, leading to elevated levels of blood sugar (glucose). The ...

A new study examining the impact of the two most commonly prescribed oral diabetes medications on the risk for heart attack, stroke and death has found the drug metformin has benefits over ...

A total of 44 patients (90 percent) successfully discontinued insulin after receiving sulfonylureas. The extent of the tolbutamide blockade of K ATP channels in vitro reflected the response seen in ...

A study comparing commonly used medications for type 2 diabetes has found that sulfonylurea drugs are associated with a reduced risk of out-of-hospital cardiac arrest compared with metformin. The ...

Neonatal diabetes can result from mutations in either Kir6.2 or SUR1 subunits of the pancreatic potassium ATP channel, which disrupt insulin release. Sulfonylureas close these channels and restore ...

WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)-- In a new post-hoc analysis presented for the first time at the American Diabetes Association (ADA) 70 th Annual Scientific Sessions, significantly more ...