Tyrosine hydroxylase (TH) catalyses the rate-limiting conversion of tyrosine to L-DOPA, the precursor of dopamine, and its regulation underpins the dynamics of dopaminergic neurotransmission across ...
Tyrosine hydroxylase deficiency (THD) is a neurometabolic genetic disorder that has so far only been diagnosed in 50 people worldwide. The symptoms include motor and cognitive impairments, such as ...
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