Medically reviewed by Doru Paul, MD Key Takeaways Low platelets can occur when your bone marrow doesn't make enough platelets ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Abstract and Introduction Review of Normal Platelet Physiology and Megakaryocytopoisis Qualitative Platelet Abnormalities Conclusion References Nitric oxide (NO) is another drug used in the neonatal ...

Macrothrombocytopenia (MTC) is a blood disorder in which blood cells called platelets are abnormally large. People with MTC also have thrombocytopenia, a low platelet count. MTC impairs blood clotting ...

Gray platelet syndrome is an inherited disease that can cause mild to moderate bleeding. People with this condition tend to bruise easily, experience nosebleeds, and may have increased surgical ...

A simple blood test for platelet activity at middle age could one day help identify people at risk for Alzheimer's disease decades ahead of time, allowing for possible preventive therapy. The ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...