For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from ...

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from ...

Researchers have identified HELQ as a key regulator of DNA replication stress responses, explaining why cells lacking the ...

DNA repair mechanism: HELQ helicase remodels stalled replication forks into stable structures, preventing harmful mutations under replication stress. Advanced imaging tool: RF-SIRF maps reversed forks ...

CANCERS ARE real biological cheats. Whereas most of the cells in a healthy animal’s body get along by following the same set of genetic rules, cancer cells shamelessly ignore them. Healthy cells, for ...

Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and ...

Men tend to lose the Y chromosome from their cells as they age. But because the Y bears few genes other than for male determination, it was thought this loss would not affect health. But evidence has ...

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...

The American Cancer Society (ACS) is awarding University of California, Santa Cruz, Professor Carol Greider with an ACS Professorship. These awards are given to preeminent cancer researchers who lead ...