Data from Phase 2a study of LAM-001 on top of standard of care in PH-ILD patients with refractory PH demonstrated clinically meaningful ...

Scientists found clock genes running inside the gut that decide when you go. Shift work breaks them.

Potassium channels in smooth muscle cells are pivotal determinants of membrane potential and contractile state. By allowing selective efflux of K+ ions, they counteract depolarising influences and ...

Calcium ions orchestrate contraction and relaxation in airway smooth muscle by regulating excitation–contraction coupling. In quiescent cells, basal cytosolic Ca2+ is maintained at nanomolar levels by ...

Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than a simple disorder of cholesterol deposition. While immune cells such as ...

A new discovery may explain why so many people abandon cholesterol-lowering statins because of muscle pain and weakness. Researchers found that certain statins can latch onto a key muscle protein and ...

Before Adam Sharples became a molecular physiologist studying muscle memory, he played professional rugby. Over his years as an athlete, he noticed that he and his teammates seemed to return to form ...

Muscle relaxers help reduce muscle stiffness and pain from conditions like cerebral palsy and lower back pain. There are two main types of muscle relaxers: antispastics and antispasmodics. Muscle ...

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded the prize for research showing how the body regulates its immune responses. By Gina Kolata and Ali Watkins Mary E. Brunkow, Fred ...

The gut undergoes peristaltic movements regulated by intricate cellular interactions. How these interactions emerge in the developing gut remains poorly explored due to a lack of model system. We here ...