In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of ...

A recent article highlights the critical importance of skeletal muscle mass in the context of medically induced weight loss, particularly with the widespread use of GLP-1 receptor agonists. These ...

Edgewise Therapeutics’ lead candidate has been shown to reduce levels of a biomarker related to skeletal muscle damage in a phase 2 trial. The biotech had been testing sevasemten, an orally ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

We hypothesize that Duchenne muscular dystrophy and autism spectrum disorder/pervasive developmental disorder co-occur with a greater than random frequency. In this study, we set out to reject the ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

The exponential rise of our aging population. The pandemic. The explosion of GLP-1s. It’s a trifecta that’s making muscle — and the serious implications of not having enough of it — part of a larger ...

Can a compound derived from a common kitchen ingredient help support muscle health during aging? A new study suggests it can. The study reveals that S-1-propenyl-L-cysteine (S1PC), a bioactive ...