The Russian missiles sought out targets from the Lviv region in western Ukraine near Poland to Kharkiv in northeast Ukraine bordering Russia. The state energy company Ukrenergo reported emergency power outages in six regions. It often shuts down production during attacks as a precaution.

Russia's military on Tuesday said it would retaliate against Ukraine after Kyiv attacked Russian regions by firing six U.S.-made ATACMS ballistic missiles, six UK-made Storm Shadow cruise missiles and launching one of the biggest drone attacks to date.

Russia launched a major ballistic and cruise missile attack on regions across Ukraine early Wednesday, targeting energy production and compelling authorities to shut down the power grid in some areas,