Thorax

Bidirectional association between visceral adiposity and obstructive sleep apnoea: longitudinal findings from the Wisconsin Sleep Cohort

Background Obstructive sleep apnoea (OSA) is a prevalent sleep disorder strongly associated with metabolic syndrome. Visceral ...
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Identification of distinct gene and miRNA expression profiles in severe early-onset COPD providing novel insights in disease pathogenesis

Objective Severe early-onset-chronic obstructive pulmonary disease (SEO-COPD) represents the most severe form of COPD that ...
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Diagnostic accuracy of focused deep venous, lung, cardiac and multiorgan ultrasound in suspected pulmonary embolism: a systematic review and meta-analysis

Objective To determine the diagnostic accuracy of point-of-care ultrasound in suspected pulmonary embolism. Design Systematic review and meta-analysis. Data sources MEDLINE, Embase, CINAHL and ...
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Using venous blood gas analysis in the assessment of COPD exacerbations: a prospective cohort study

Introduction Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are ...
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Changes in right heart haemodynamics and echocardiographic function in an advanced phenotype of pulmonary hypertension and right heart dysfunction associated with pulmonary ...

2 Division of Rheumatology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA 3 Cardiovascular Division, Department of Medicine, Perelman School of Medicine at the University of ...
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British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...
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Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial

1 Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium 2 Department of Respiratory Medicine, OLV Ziekenhuis, Aalst, Belgium 3 Department of Respiratory Medicine, AZ Groeninge, ...
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Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia

NHLI Cardiovascular Sciences, Faculty of Medicine, Imperial College London, UK Background: Brain abscesses and ischaemic strokes complicate pulmonary arteriovenous malformations (PAVMs). At risk ...
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Time trends in allergic disorders in the UK

1 Lung and Asthma Information Agency, Division of Community Health Sciences, St George’s, University of London, UK 2 Division of Community Health Sciences: GP Section, University of Edinburgh, UK 3 ...
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Prevalence, diagnosis and relation to tobacco dependence of chronic obstructive pulmonary disease in a nationally representative population sample

1 Cancer Research Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK 2 Division of Epidemiology and Public Health, University of ...
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COPD exacerbations · 1: Epidemiology

The epidemiology of exacerbations of chronic obstructive pulmonary disease (COPD) is reviewed with particular reference to the definition, frequency, time course, natural history and seasonality, and ...