After six months of treatment, medicines called 'biologics' seem to work best to clear raised patches of psoriasis on the skin. Longer studies are needed to assess the benefits and potential unwanted ...

What are the benefits and risks of natalizumab (NTZ) in people with multiple sclerosis (MS)?

There is limited evidence to support the use of tumor necrosis factor-alpha antagonists (anti-TNF) therapy for induction of remission in children with Crohn's disease. • More well-designed studies are ...

Improvement in IIM activity, as measured by the International Myositis Assessment and Clinical Studies Group (IMACS) definitions of improvement (DOI), may be more likely with abatacept treatment ...

Due to a lack of robust evidence, we could not determine the benefits and unwanted effects of hospital networks (organised trauma systems) or individual hospitals (designated trauma centres) that are ...

We found nine studies involving a total of 689 women with stress urinary incontinence. Nine studies compared vaginal lasers to either sham or lubricant, and one study compared vaginal lasers to ...

Part 3 provides considerations for tackling systematic reviews from different perspectives, such as when thinking about specific populations, or complex interventions, or particular types of outcomes.

I receive royalties from Wiley for my book 'Individual Participant Data Meta-Analysis', and from OUP for my book 'Prognosis Research In healthcare'. I receive consultancy fees from BMJ for statistical ...

Cochrane Interactive Learning is our comprehensive course on how to conduct a systematic review. Equip yourself, or your staff and students, with the skills to conduct systematic reviews through ...

COS schedules with the additional use of tamoxifen or letrozole are commonly chosen as an alternative regimen in young women with ER positive breast cancer who undergo COS for oocyte or embryo ...

I receive payment for training courses that I run alone and with collaborators about searching as part of the systematic review process. I receive contracts from academic organisations and consultancy ...

Convicted drink drivers are sometimes offered the choice of a standard punishment, or for an alcohol ignition interlock to be fitted to their car for a fixed period. To operate a vehicle equipped with ...