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  1. Sickle Cell Disease - Symptoms | NHLBI, NIH

    Aug 20, 2024 · Sickle Cell Disease Fact Sheet Learn basics about sickle cell disease, including symptoms, how to prevent health problems and treatment options.

  2. Sickle Cell Disease - Treatment | NHLBI, NIH

    Sep 30, 2024 · Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow …

  3. Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  4. How Sickle Cell Disease May Affect Your Health - NHLBI, NIH

    Aug 22, 2024 · It is usually different from crisis pain or the pain that results from organ damage, and thus is treated differently. Vitamin deficiency: People with sickle cell disease are at higher risk for nutrient …

  5. Managing Pain With Sickle Cell Disease People with sickle cell disease (SCD) may experience pain in different ways. The sickled cells that give the disease its name can lead to pain throughout the body …

  6. Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH

    Aug 20, 2024 · Who can get sickle cell disease? Sickle cell disease is a genetic disorder caused by mutations in hemoglobin genes, leading to a faulty hemoglobin protein, called hemoglobin S. …

  7. In consultation with a sickle cell expert, transfuse people who have acute splenic sequestration and severe anemia to raise the hemoglobin to a stable level, while avoiding over-transfusion.

  8. Aug 16, 2002 · Foreword The purpose of the “Evidence-Based Management of Sickle Cell Disease: Expert Panel Report (EPR), 2014” is to synthesize the available scientific evidence on sickle cell …

  9. Evidence-Based Management of Sickle Cell Disease: Expert Panel …

    The purpose of these guidelines is to help people living with sickle cell disease (SCD) receive appropriate care by providing the best science-based recommendations to guide practice decisions. …

  10. Sickle Cell Disease - Sickle Cell Trait | NHLBI, NIH

    Aug 22, 2024 · Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent. People who have sickle cell …