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One of the biggest misunderstandings in this debate is the idea that anyone is claiming every child who takes acetaminophen will develop autism. That is not the hypothesis. The hypothesis is that a small subset of susceptible children, perhaps 1 to 3% of the population, cannot safely handle acetaminophen exposure. In those children, more of acetaminophen's well known toxic metabolite, NAPQI, may be generated or inadequately detoxified, leading to biological injury. This is not a claim about all
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